AI is moving from demos into everyday systems. This issue covers Gemini notebooks, Anthropic’s managed agents and cyber push, local AI momentum with Gemma 4, and healthcare tools already changing workflows.

Google is rolling out Notebooks in Gemini, giving you dedicated project hubs where you can organize tasks, pull in past chats, and attach relevant files as sources. The feature launches this week for AI Ultra, Pro, and Plus subscribers on the web, with mobile, more European regions, and free users coming next.

What’s new

Why this matters for builders

Notebooks transform Gemini into a centralized workspace, integrating research and past work for reliable planning, writing, and development with NotebookLM.

Some people use Claude to write emails. Others use it to basically run their entire business while they play Wordle.

This isn't just ChatGPT's cooler cousin. It's the AI that's quietly revolutionizing how smart people work – writing entire business plans, planning marketing campaigns, and basically becoming the intern you never have to pay.

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Anthropic has launched Project Glasswing with partners like AWS, Apple, and Google to enhance software security against AI-driven cyber threats. Using the Claude Mythos Preview model, the initiative aims to empower defenders by providing $100M in usage credits and $4M in open-source security funding as partners scan for zero-day vulnerabilities.

Google's Gemma 4 models, released under Apache 2.0, achieved over 10 million downloads in the first week, contributing to 500 million total Gemma pulls. Community benchmarks show 25–50 tokens/sec on a 16GB MacBook Air. Builders are fine-tuning Gemma 4’s text, vision, and audio variants on Apple Silicon with mlx-tune.

Meta's Muse Spark, developed by Meta Superintelligence Labs, is a multimodal reasoning model with tool-use, visual chain-of-thought, and multi-agent orchestration. It excels in perception, reasoning, health, and agentic tasks, supported by the Hyperion data center. It includes a Contemplating mode for advanced reasoning and is available on meta.ai, with a private API preview for select developers.

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A Dutch cancer center used AI reconstruction to cut MRI scan times from 23 to 9 minutes, increasing capacity, reducing motion blur, and easing patient strain without extra staff hours. This allows 18 more scans per week and offers radiology teams more flexibility for urgent cases.

This issue also covers one‑click cardiac MRI planning, instant meal‑scanning nutrition apps, AI‑powered pantry remedies, and a sugarcane‑derived protein that protects enamel after radiotherapy.

Anthropic is rolling out Managed Agents, a new suite of composable APIs that lets teams build and deploy cloud‑hosted agents without managing infrastructure. Developers define tasks, tools, and guardrails, while Anthropic handles sandboxing, permissions, orchestration, and long‑running sessions. The public beta is live today on the Claude Platform.

What’s new

Why this matters for builders

Managed Agents simplify infrastructure tasks, allowing quick deployment of agents. With Claude-tuned orchestration, teams achieve higher success, faster iteration, and smoother transitions from prototype to production.

Hedra Character‑3 lets you create a fully animated video with gestures, expressions, and voice in minutes by uploading a photo and adding a script or audio, while automatically managing motion, timing, and character consistency.

How it works:
1️⃣Open Hedra’s video tool and select Character‑3
2️⃣Upload a reference image or describe your character
3️⃣Add a script or synthetic voice for narration
4️⃣Choose gestures, pacing, and emotional tone
5️⃣Generate, refine, and export your final video

Try Hedra Character-3 →

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McKinsey’s Skill Change Index shows AI is transforming high‑value human abilities like negotiation, problem‑solving, leadership, and judgment into hybrid workflows where people coordinate across agents, frame problems instead of executing them, and guide mixed human‑AI teams.

In this issue, we cover OpenAI’s $122B raise and its push toward a unified AI superapp, Anthropic making Microsoft 365 connectors free for all Claude users, and the major AI events builders should track this week.

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