📊 Claude Just Landed in Excel & PowerPoint

✨ Welcome back, Entrepreneurs

This issue captures: Claude bringing unified context and one-click skills to Excel and PowerPoint, NVIDIA pushing open agentic models with Nemotron 3 Super, Perplexity launching enterprise workflow orchestration, and Anthropic expanding research and global reach. Plus: AIHealthTech insights on brain-network diagnostics and new tools helping creators ship content faster.

📊 Claude x Microsoft 365: Unified Context + One‑Click Skills Across Excel and PowerPoint

Anthropic is upgrading Claude for Excel and PowerPoint with shared context, one-click actions, and seamless data integration. It supports Amazon Bedrock, Google Cloud’s Vertex AI, and Microsoft Foundry for flexible enterprise use.

Highlights

• Shared context across all open Excel and PowerPoint files

• Cross‑app actions: read cells, write formulas, merge data, update slides

• One‑click skills for financial models, data cleaning, comps, and deck building

• Starter skills for Excel and PowerPoint via the Financial Analysis plugin

• Persistent instructions for formatting, templates, and team‑wide preferences

Impact

These updates streamline transitions from analysis to presentation, accelerating financial modeling, deck creation, and data cleanup while maintaining standards. With flexible deployment and Microsoft 365 Copilot integration, organizations can boost workflow efficiency and quality.

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​🔥Big AI moves

🔹Anthropic launches The Anthropic Institute: A new hub for understanding powerful AI

Anthropic launched The Anthropic Institute, led by co-founder Jack Clark, to study AI's impact on work, law, and society. It combines model testing, economic analysis, and real-world impact studies, providing insights for policymakers, researchers, and the public as Anthropic develops advanced systems.

🔹NVIDIA launches Nemotron 3 Super: a new open model built for large‑scale agentic AI

NVIDIA's Nemotron 3 Super is a 120B-parameter hybrid Mamba-Transformer model with 12B active parameters, offering up to 5× higher throughput for multi-agent systems. It features a 1M-token context window, advanced reasoning, and open weights, allowing for faster, more accurate agentic workflows across various deployments.

🔹Anthropic opens a Sydney office: a new hub for AI collaboration in Australia & New Zealand

Anthropic is opening a Sydney office, its fourth in Asia-Pacific, to meet growing demand in Australia and New Zealand. The team will enhance partnerships, collaborate on AI projects, and work with enterprises, startups, and researchers using Claude. With high regional usage, Anthropic is exploring local compute capacity to support the expanding AI ecosystem.

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🧠 AIHealthTech Insider: Brain‑network AI sharpens major depression detection

A model featured by Nature India uses enriched brain-signal features and demographic data to identify major depressive disorder by analyzing altered connectivity patterns in brain networks, rather than isolated regions.

This issue explores AI's impact on diagnostic precision in areas like brain-network models for depression, valve-disease detection, coronary-plaque automation, DR screening economics, and the safety gap between consumer chatbots and clinical systems.

⚙️ Perplexity x Computer for Enterprise: Multi‑Model Workflow Orchestration for Teams

Perplexity is launching Computer for Enterprise, a workflow engine for multi-step tasks in research, coding, design, and deployment. It utilizes 20 specialized models, connects to 400+ apps including Slack, and offers shared task execution, premium research sources, and tools for custom skills and integrations.

Highlights

• Multi‑step workflows spanning research, coding, design, and deployment

• Routing across 20 specialized models for parallel task execution

• 400+ app integrations, including Slack channels and DMs

• Access to premium sources like CB Insights, PitchBook, and Statista

• Organizational skills, shared connectors, and bring‑your‑own MCP support

Impact

Computer for Enterprise provides organizations with a unified system for complex work, integrating research, coding, automation, premium data, and collaborative Slack workflows. This enables faster execution, shared context, and scalable operations.

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⚙️ Sunday Special: GPT‑5.4’s agent‑first leap reshapes how real work gets done

This issue highlights the week’s most practical signals for builders — from GPT‑5.4’s workflow‑ready upgrades and NVIDIA’s agentic model push to high‑impact AI events, fast upskilling paths, and career moves defining the next generation of AI‑native operators.